Sareum - Specialists in Structure-based Drug Discovery - Investors

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Sareum Holdings PLC

(“Sareum” or “the Company”)

Placing to raise £315,000

Sareum (AIM: SAR), the specialist cancer drug discovery business, is pleased to announce it has conditionally raised £315,000, before expenses, by way of a placing by Hybridan LLP of 157,500,000 new ordinary shares of 0.025p each in the capital of the Company (the “Placing Shares”) at 0.2p per share.

Sareum intends to use the proceeds of the Placing to progress its cancer research programmes and for general working capital.

Application has been made to the London Stock Exchange for the Placing Shares to be admitted to trading on AIM and it is expected that admission will become effective and trading will commence on 11 September 2009. The Placing Shares will rank pari passu with the existing ordinary shares of the Company.

Following the admission of the Placing Shares to trading on AIM, the Company will have a total of 975,598,000 shares in issue.

Tim Mitchell, Founder and CEO commented:

“We are pleased to have been able to raise these funds despite the difficult economic climate. The placing will provide additional funds to progress our pipeline of cancer research programmes.”

Enquiries:

Sareum Holdings plc
Tim Mitchell	01223 497 700

John East & Partners Limited, a subsidiary of Merchant Securities PLC
Simon Clements/Bidhi Bhoma	020 7628 2200

Hybridan LLP
Claire Noyce/Stephen Austin	020 3159 5085

This announcement is for information purposes only and does not constitute an offer or invitation to acquire or dispose of any securities or investment advice in any jurisdiction.

Hybridan LLP, which is authorised and regulated in the United Kingdom by the Financial Services Authority, is acting exclusively for the Company and no-one else in connection with the Placing and will not be responsible to anyone other than the Company for providing the protections afforded to clients of Hybridan LLP or for providing advice in relation to the Placing or any transaction or any other matters referred to herein.

Past performance is no guide to future performance and persons needing advice should consult an independent financial adviser.

The information contained in this announcement is not for release, publication or distribution, directly or indirectly, to persons in the United States, Australia, Canada, Japan or the Republic of South Africa or in any jurisdiction in which such publication or distribution is unlawful. The Placing Shares have not been and will not be registered under the United States Securities Act of 1933, as amended, or under the laws of any state of the United States. This announcement does not constitute an offer to sell or issue, or the solicitation of an offer to buy or subscribe for, securities in the United States, Australia, Canada, Japan or the Republic of South Africa or in any jurisdiction in which such offer or solicitation is unlawful and should not be relied upon in connection with any decision to acquire Placing Shares or other securities in the capital of the Company. There will be no public offer of Placing Shares in the United Kingdom or elsewhere.

Notes for editors:

About Sareum Holdings plc

Sareum is a drug discovery company, headquartered in Cambridge UK, that is focused on producing targeted small molecule therapeutics to address unmet medical needs, primarily in cancer.

Sareum aims to successfully deliver drug candidates for licensing to pharmaceutical and biotechnology companies at the pre-clinical or early clinical trials stage.

Sareum Holdings plc joined the AIM market of the London Stock Exchange in October 2004, trading under the symbol SAR. For further information, please visit www.sareum.co.uk