News & Events - Patents

Sareum scientists have over 200 years drug discovery experience, selected patents include;

Spleen Tyrosine Kinase Catalytic Domain: Crystal Structure and Binding Pockets Thereof. Williams D.H., Lamers, M.B.A.C., Smith, S. and Cherry, M. WO2004035604 (2004).
Crystal Structure of Angiotensin Converting Enzyme 2. Pantoliano, M.W., Ryan, M.D., Staker, B.L., Prasad, G.S., Tang, J., Menon, S.P., Towler, P.S., Williams, D.H. and Fisher, M. WO2004023270 (2004).
Preparation of benzimidazoles and analogs and their use as protein kinase inhibitors. Edwards, M.L., Cox, P.J., Amendola, S., Deprets, S.D., Gillespy, T.A., Edlin, C.D., Morley, A.D., Gardner, C.J., Pedgrift, B., Bouchard, H., Babin, D., Gauzy, L., Le Brun, A., Majid, T.N., Reader, J.C., Payne, L.J., Khan, N.M. and Cherry, M. WO2003035065 (2003).
Diarylurea compounds and derivatives as Chk-1 inhibitors for the treatment of cancer. Boyle, R.G., Imogai J.H., and Cherry, M. WO03101444 (2003).
Crystal Structure of a mutant of Cathepsin S enzyme. Lamers. M.B.A.C., Williams, D.H., Turkenburg, J.P. and Hubbard, R.E. US2003143714 (2003).
2-Amino-4H-3,1-benzoxazin-4-one derivatives for the treatment of obesity. C Dunk, H Hodson, T Mitchell, R Palmer, R Downham and B Carr. WO0040247 (2000).
2-Oxy-4H-3,1-benzoxazin-4-one derivatives for the treatment of obesity. C Dunk, H Hodson, T Mitchell, R Palmer, R Downham and B Carr. WO0040569 (2000).